JPRN-jRCT2031200182
Completed
Phase 1
A Phase 1, Randomized, Double-blind, Placebo-controlled Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of BPN14770, A Randomized, Open-label, 2-Period Crossover Study to Assess the Effect of Food on the Pharmacokinetics of BPN14770, and An Open-label, Add-on Study to Assess the Drug-Drug Interaction Between BPN14770 and Midazolam and Between BPN14770 and Donepezil Hydrochloride, in Healthy Young and/or Elderly Participants
agata Tsutae0 sites112 target enrollmentNovember 6, 2020
ConditionsHealth Condition
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Health Condition
- Sponsor
- agata Tsutae
- Enrollment
- 112
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Healthy Japanese or Caucasian adult participants aged \>\= 20 to \<\= 55 at the time of signing the informed consent form
- •2\. Healthy Japanese elderly participants aged \>\= 65 to \>\= 75 at the time of signing the informed consent form
Exclusion Criteria
- •History or presence of cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrinological, hematological, or neurological disorders capable of significantly altering the absorption, metbolism, or elimination of drugs; constituting a risk when taking the study intervention; or interfering with the interpretation of data (depending on the judgement of investigator or subinvestigator)
Outcomes
Primary Outcomes
Not specified
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