A Longitudinal Study of Multimodal Resonance Imaging in Stroke Patients
- Conditions
- Stroke
- Registration Number
- NCT02024503
- Lead Sponsor
- Zhongda Hospital
- Brief Summary
Imaging of the ischaemic penumbra with a particular diffusion-weighted imaging (DWI)/ perfusion-weighted imaging (PWI) mismatch is a promising approach to the selection of patients with acute ischaemic stroke for trials of intervention. The investigators want to apply multimodal resonance imaging methods such as functional magnetic resonance imaging ( fMRI), diffusion tensor imaging (DTI), arterial spin labeling (ASL) to guide treatment and predict the prognosis of stroke.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 800
Time from the onset of stroke till hospital within 24 hours. With clinical characteristics such as hemiplegia, headache. Willing and able to comply with the study procedures and provide written informed consent to participate in the study.
Patients must understand the nature of the study and give informed consent.
The onset of stroke out of 24 hours. Pregnant women. Patients with intracranial metallic bodies from prior neurosurgical procedure, implanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, TENS unit or ventriculoperitoneal shunt.
Past history of seizures within one year or unexplained loss of consciousness. Family history of epilepsy.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Functional recovery Participants will be followed till die or lost to follow-up,an expected average of three year.
- Secondary Outcome Measures
Name Time Method Over survival Participants will be followed till die or lost to follow-up,an expected average of three year Time from stenting to the day when the patients died or lost to the follow-up
Trial Locations
- Locations (1)
Zhongda Hospital,Southeast University
🇨🇳Nanjing, Jiangsu, China