TCTR20230418007
Unknown
Phase 4
A pilot study of efficacy and safety of microneedling-assisted topical botulinum toxin A for the treatment of enlarged facial pores: a split-face randomized-controlled pilot study
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Enlarged facial pores
- Sponsor
- Faculty of Medicine Siriraj Hospital, Mahidol University
- Enrollment
- 25
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Thai descendants
- •2\. There are enlarged pores on both cheeks. By definition, enlarged pores must be visible to the naked eye (visible topographic enlarged facial pores) at a distance of 30 cm and examined by two dermatologists with a consensus.
Exclusion Criteria
- •1\. Pregnant, breastfeeding, or after giving birth for no more than three months or plan to become pregnant during six months.
- •2\. Using vitamin A compounds or chemical peeling agents or injecting botulinum toxin on the cheek area in the last six months
- •3\. History of allergy to anesthetics or botulinum toxin
- •4\. History of hypertrophic scars or keloids
- •5\. Open wounds, infected skin, or skin rashes on the face
- •6\. Having underlying diseases such as diabetes, collagen\-related disorders, immunodeficiencies, or having an underlying condition that the researcher considers to be unsafe if participating in the program, such as epilepsy
- •7\. History of regularly using steroids or smoking.
- •8\. History of using anticoagulants, antiplatelet agents, or ginkgo leaf extract.
- •9\. Volunteers with an implanted pacemaker with an implanted metallic device.
Outcomes
Primary Outcomes
Not specified
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