Do Hypertonic Solutions Have an Impact on Nasal Eosinophilia in Allergic Rhinitis Patients?
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- The number of eosinophils in nasal secretions
研究概览
简要总结
The purpose of this study is to assess the effectivity of using hypertonic nasal solutions alone on the symptom scores and nasal eosinophil levels of allergic rhinitis patients, retrospectively.
详细描述
The medical records of the patients who admitted to outpatient clinic of otorhinolaryngology department of a tertiary referral center were retrospectively investigated. The symptom scores and nasal eosinophil levels of the patients were recorded. Patients using hypertonic solutions alone or steroid nasal spray alone were compared.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with positive Prick's test to at least one allergen and diagnosed as having allergic rhinitis were included
- •Patients who used hypertonic nasal solution alone for at least one month were included as sthe study group
- •Patients who used nasal steroid spray alone or at least one month were included as sthe study group
排除标准
- •Patients with a history of asthma, urticeria, eczama, diabetes mellitus, hypertension, COPD and other systemic diseases were excluded
结局指标
主要结局
The number of eosinophils in nasal secretions
时间窗: The number of eosinophils in nasal secretions that was counted before the therapy and after the first month of therapy would be recorded
次要结局
- Sinonasal Outcome Test (SNOT-22) questionairre scores(SNOT-22 scores obtained before the treatment and after the first month of treatment would be recorded)
研究者
Zafer Ciftci
Assist. Prof., M.D.
Namik Kemal University