Interest of Contact Precautions for Preventing Micro-organisms Acquisition in Patients Hospitalized in Infectious Disease Unit of University-affiliated Hospital in Rennes

Terminated

• Conditions: Patients Hospitalized in Infectious Disease

• Registration Number: NCT01562769
• Lead Sponsor: Rennes University Hospital

Brief Summary

Application of isolation (=contact precautions) in hospitalized patients is recommended when patient is colonized (or infected) by micro-organism known for its outbreak capacity or high pathogenicity. It allows the reinforcement of universal precautions (=standard precautions) in order to control patient-to-patient micro-organisms transmission. Recently, the efficacy of this measure is questioned and its impact on patient care seems deleterious.

In a particular context of Infectious Disease Unit, where standard precautions are handled (favorable architecture and appropriate practice for hand hygiene), assessment of contact precautions to reduce the incidence of acquired bacteria during hospitalization would be of interest.

The investigators design a non-inferiority comparative study to measure the colonization pressure in patients hospitalized in two different parts of the department: one unit only with standard precautions applied (intervention) and one unit with contact precautions (control) as current routine care.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03
• Study First Submitted: 2012-03-22
• Study First Submitted QC: 2012-03-23
• Study First Posted: 2012-03-26
• Primary Completion: 2015-04
• Status Verified: 2015-05
• Study Completion: 2015-06
• Last Update Submitted: 2015-08-20
• Last Update Posted: 2015-08-21

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Patient hospitalized in Infectious Diseases Unit during the study period in one of the selected part of the unit participating to the study
• Patient informed about the study protocol and approved to participate.

Exclusion Criteria

• Patient requiring isolation prescription type "air" or "droplet"
• Patient hospitalized in the central sector of the building (including 4 bedrooms in depression negative service)
• Patient colonized with bacteria producing carbapenemase, multi-resistant Acinetobacter baumanii or Vancomycin-Resistant Enterococcus.
• Patients under legal protection (juridical protection, legal guardianship) or persons on juridical detention.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Acquisition rate of micro-organisms	2 years	Acquisition rate using bacteriological sampling (nose and anus) at admission and at the day of discharge in each patient hospitalized in the department.

Secondary Outcome Measures

Name	Time	Method
Utilization of aprons and gloves in each group	2 years
Number of infections acquired during hospitalization in each group	2 years
Consumption of hydro-alcoholic rub in each group	2 years

Trial Locations

Locations (1)

Rennes University Hospital; 🇫🇷 Rennes, Brittany, France