The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 86
- 主要终点
- pain score using Visual Analogue scale, ranging from 0 (minimum) and 10 (maximum), 3 and below showing no pain and scores above 3 showing moderate to severe pain.
研究概览
简要总结
This double-blinded randomized control trial aims to analyze the effect of low dose Ketamine on narcotic consumption, in patients undergoing Laparoscopic cholecystectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
盲法说明
Double blinded
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •all ASA 1 and 2 patients undergoing Laparoscopic Cholecystectomy electively.
排除标准
- •Hepatic and renal disease and ASA 3 and 4 patients.
研究组 & 干预措施
Ketamine group (Group K)
Group K was given ketamine @ 0.5mg/kg (prepared by dilution in 0.9% normal saline in 10 ml syringe) at the time of wound closure.
干预措施: Ketamine Hydrochloride (Drug)
Saline group (Group S)
Group S was given saline in 10 ml syringe
干预措施: Ketamine Hydrochloride (Drug)
结局指标
主要结局
pain score using Visual Analogue scale, ranging from 0 (minimum) and 10 (maximum), 3 and below showing no pain and scores above 3 showing moderate to severe pain.
时间窗: Baseline on arrival in the post anaesthesia care unit and then every fifteen minutes unto one hour
Change in pain score using Visual Analogue Scale
次要结局
- narcotic consumption in the post operative anaesthesia care unit(postoperatively, after arrival in the post anaesthesia care unit at every fifteen minutes unto one hour)
研究者
Dr. Saima Rashid
Senior Instructor
Aga Khan University