Embryo Selection Using Non-invasive Metabolomic Analysis Indicates Improvement in Implantation Rates With Fetal Cardiac Activity
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Embryo Viability
- Sponsor
- Eugonia
- Enrollment
- 125
- Locations
- 1
- Primary Endpoint
- Implantation rates
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Metabolomics was recently introduced in human IVF for non-invasive identification of viable embryos with the highest developmental competence. The investigators intended to investigate if embryo assessment using non-invasive metabolomic profiling leads to increased implantation rates compared to routine morphology evaluation alone.
Detailed Description
Metabolomics was recently introduced in human IVF for non-invasive identification of viable embryos with the highest developmental competence. The aim of the present study was to determine whether embryo selection using non-invasive metabolomic profiling as an adjunct to morphology leads to increased implantation rates compared to routine morphology evaluation alone.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients with at least 4 fertilized oocytes
Exclusion Criteria
- •patients with less that 4 fertilized oocytes
Outcomes
Primary Outcomes
Implantation rates
Time Frame: 6 weeks of pregnancy
To compare non-invasive metabolomic profiling and the traditional method of morphology assessment for embryo selection in terms of implantation and pregnancy rates in a clinical IVF program.