Research on clinical intervention of TCM Prevention and treatment of MCI based on artificial intelligence big data platform health management

Phase 1

• Conditions: MCI

• Registration Number: ITMCTR2000003810
• Lead Sponsor: onghua Hospital Affiliated to Shanghai University of traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Aged 40-85 years old;
2. chief complaint of memory impairment and memory difficulty confirmed by others;
3. Mini Mental State Examination (MMSE) score of 24-30 points;
4. Hamilton Depression Rating Scale score <=12 points (17 items);
5. no obvious cerebrovascular disease: Hachinski ischemic score (his) score <=4;
6. CT or MRI within 12 months before screening There was no evidence of infection, infarction or other focal injury, and no suggestive clinical symptoms related to neurological diseases; lacunar infarction in a non critical brain area could be allowed and not be considered to affect the cognitive impairment of the subjects;
7. sufficient visual and auditory resolution was required for neuropsychological tests;
8. TCM Syndrome Differentiation for kidney essence deficiency, Qi and blood deficiency patients.

Exclusion Criteria

1. Positive dementia: MMSE <=24 points or meeting the DSM - IV dementia diagnostic criteria;
2. obvious cerebrovascular diseases: his greater than 4 points or clinical cerebral infarction;
3. moderate depression or another mental disease in line with DSM - IV standard in the past two years;
4. the past 2 years He had a history of alcohol or drug abuse or addiction (DSM - IV standard) within one year;
5. history of schizophrenia (DSM - IV standard);
6. any obvious neurological diseases such as Parkinson's disease, Huntington's disease, normal intracranial pressure hydrocephalus, brain tumor, progressive supranuclear palsy, epilepsy, subdural edema, multiple sclerosis, severe head trauma, with persistent neurological deficits or known structural brain abnormalities;
7. can not follow the research procedure.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MoCA;MMSE;