跳至主要内容
临床试验/CTRI/2020/09/028052
CTRI/2020/09/028052尚未招募2/3 期

A randomised clinical study for efficacy of Kalingadi Vati in the management of Arsha with special reference to 1st and 2nd degree Haemorrhoids

Ayurved Mahavidyalaya Nashik1 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2020年9月28日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
74
试验地点
1
主要终点
Decrease in bleeding tendancy

研究概览

简要总结

According to Ayurveda apathya aahar,vihar leads to vatadi dosha dushti at the guda vali (anal region), pradhandhamani (venous supply),mansadhara kala and vitiates twaka,mansa,rakta,meda resultingin annavaha strotas dushti,agnimandya and arsha

According tomodern science, haemorrhoid is engorgement of haemorrhoidal venous plexuscharacterized by bleeding per rectum,constipation,pain,prolapseand discharge.A growing inclination for fast food, faulty food habbits, spicy junk foods,aerated cold drinks, low intake of fiber rich diet.Stressfulprofessions,busylifestyle, constipation, insomnia that’s all affect the health of the body.Because of all these things constipation occurs. Long duration of constipationand prolonged straininglead to engorgement of veins in anal canal and givesbirth to haemorrhoids.

In modernscience, haemorrhoids have very limited options for treatment which are mostlydifferent surgical modalities like Lord’s anal dilatation, Cryosurgery, laserhaemorrhoidectomy, injection sclerotherapy, rubber band ligationetc. But arsha disease is mainly related to sedentary lifestyle and hampereddigestive system.So even after the surgical treatment and modern conservativetreatment there is probability of recurrenece andpostoperativepain is verytroublesome. Anal stenosis and incontinence are deadful complaints. The cost ofsurgery is also relatively highso patients are not readily willing for surgery.

According toSushrut Samhita and Vagbhata Samhita, there are fourtreatment modalities of arsha i.e. bhaishajchikitsa (internal medicine), ksharakarma (chemical cauterization), Agnikarma (thermal cauterization) and shastrakarma (surgicaltechnique). Agnimandya is the main etiological factor of arsha.One important effective formulation is kalingadi vati explained inAshtangahrudaya. The ingredients of this vati areKalinga,Langali,Pippali,Apamarga,Bhunimba etc. The properties of these dravyasleads to Agnideepana, Arshoghna, Pachan, Shothahar, Shoolghna and Sthambhan.Hence it can break down the samprapti of arsha disease. So we have decided tostudy the efficacy of kalingadivati in the management of arsha which is verycost effective and easily available. Ayurveda Samhita provideus the opportunity to treat arsha with cost effective medication instead ofsurgical procedure. Raktastrava and agnimandya is the main complaint of thepatient in the arsha disease. According to ayurvedic Samhita there are twotypes of arsha that is Stravi and Astravi. Kalingadivati seems tobe an ideal formulation which can cause Agnideepana also Raktstambhan.Tilldateno study has been conducted on kalingadivati.Therefore it was decided to takeup this study.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
17.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patient having clinical features of Arsha Agnimandya.
  • Saraktmalpravritti.
  • Malavshthambha.

排除标准

  • Diagnosed case of Carcinoma of rectum large intestine rectal polyps prolapse of rectum fistula in ano crohns disease fissure in ano Pregnant women and lactating mother Patients having systemic diseases like liver cirrhosis portal hypertension Severe anaemic patient Bleeding disorders like haemophilia and purpura.

结局指标

主要结局

Decrease in bleeding tendancy

时间窗: 30 days

Relief in anorectal pain and inflammation

时间窗: 30 days

次要结局

  • Relief in constipation(Relief in anorectal itching)

研究者

发起方
Ayurved Mahavidyalaya Nashik
申办方类型
Other [State Govt Grant in aid Institute]

研究点 (1)

Loading locations...

相似试验