Study of effect of Kalingadi Vati in piles

Phase 2/3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2020/09/028052
• Lead Sponsor: Ayurved Mahavidyalaya Nashik

Brief Summary

According to Ayurveda apathya aahar,vihar leads to vatadi dosha dushti at the guda vali (anal region), pradhandhamani (venous supply),mansadhara kala and vitiates twaka,mansa,rakta,meda resultingin annavaha strotas dushti,agnimandya and arsha

According tomodern science, haemorrhoid is engorgement of haemorrhoidal venous plexuscharacterized by bleeding per rectum,constipation,pain,prolapseand discharge.A growing inclination for fast food, faulty food habbits, spicy junk foods,aerated cold drinks, low intake of fiber rich diet.Stressfulprofessions,busylifestyle, constipation, insomnia that’s all affect the health of the body.Because of all these things constipation occurs. Long duration of constipationand prolonged straininglead to engorgement of veins in anal canal and givesbirth to haemorrhoids.

In modernscience, haemorrhoids have very limited options for treatment which are mostlydifferent surgical modalities like Lord’s anal dilatation, Cryosurgery, laserhaemorrhoidectomy, injection sclerotherapy, rubber band ligationetc. But arsha disease is mainly related to sedentary lifestyle and hampereddigestive system.So even after the surgical treatment and modern conservativetreatment there is probability of recurrenece andpostoperativepain is verytroublesome. Anal stenosis and incontinence are deadful complaints. The cost ofsurgery is also relatively highso patients are not readily willing for surgery.

According toSushrut Samhita and Vagbhata Samhita, there are fourtreatment modalities of arsha i.e. bhaishajchikitsa (internal medicine), ksharakarma (chemical cauterization), Agnikarma (thermal cauterization) and shastrakarma (surgicaltechnique). Agnimandya is the main etiological factor of arsha.One important effective formulation is kalingadi vati explained inAshtangahrudaya. The ingredients of this vati areKalinga,Langali,Pippali,Apamarga,Bhunimba etc. The properties of these dravyasleads to Agnideepana, Arshoghna, Pachan, Shothahar, Shoolghna and Sthambhan.Hence it can break down the samprapti of arsha disease. So we have decided tostudy the efficacy of kalingadivati in the management of arsha which is verycost effective and easily available. Ayurveda Samhita provideus the opportunity to treat arsha with cost effective medication instead ofsurgical procedure. Raktastrava and agnimandya is the main complaint of thepatient in the arsha disease. According to ayurvedic Samhita there are twotypes of arsha that is Stravi and Astravi. Kalingadivati seems tobe an ideal formulation which can cause Agnideepana also Raktstambhan.Tilldateno study has been conducted on kalingadivati.Therefore it was decided to takeup this study.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-09-17
• Study Start: 2020-09-28

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

• Patient having clinical features of Arsha Agnimandya.
• Saraktmalpravritti.
• Malavshthambha.

Exclusion Criteria

Diagnosed case of Carcinoma of rectum large intestine rectal polyps prolapse of rectum fistula in ano crohns disease fissure in ano Pregnant women and lactating mother Patients having systemic diseases like liver cirrhosis portal hypertension Severe anaemic patient Bleeding disorders like haemophilia and purpura.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease in bleeding tendancy	30 days
Relief in anorectal pain and inflammation	30 days

Secondary Outcome Measures

Name	Time	Method
Relief in constipation	Relief in anorectal itching

Trial Locations

Locations (1)

Arogyashala Rugnalaya Nashik; 🇮🇳 Nashik, MAHARASHTRA, India

Arogyashala Rugnalaya Nashik

🇮🇳Nashik, MAHARASHTRA, India

Dr Deepali Ajitrao Kolnure

Principal investigator

9284202284

kdeepalida@gmail.com