Efficacy of Parasagittal Oblique Approach to Anterior Quadratus Lumborum Block for Gynecologic Surgery: A Randomized Controlled Trial

Phase 4

• Conditions: Healthy female who schedule for open gynecologic surgery; Gynecologic surgical procedure, Acute pain, Nerve block, Quadratus lumborum block

• Registration Number: TCTR20210625003
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-25
• Study Completion: 2022-07-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Female
• Target Recruitment: 69

Inclusion Criteria

1 Patients with American Society of Anesthesiologists (ASA) physical classification I-III
2 Scheduled for elective open gynecologic surgeries which include total abdominal hysterectomy , total abdominal hysterectomy with bilateral salpingo-oophorectomy , myomectomy or ovarian cystectomy

Exclusion Criteria

1 Patient who allergic local anesthetic or study drugs
2 Patient with chronic pain or chronic use of opioid (more than 2 weeks within 1-month
3 Patient who has local skin infection at injection site
4 Body mass index > 35 kg/m2
5 History of liver dysfunction (AST, ALT > 50 IU/L) or renal impairment (CrCl < 60 mg/ml), Coagulopathy (platelets < 100,000/mL or INR > 1.4)
6 Patient who cannot assess pain score or unable to operate intravenous-patient controlled analgesia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
24 hours morphine consumption 1, 6, 12, 24 hours after surgery total mg of morphine

Secondary Outcome Measures

Name	Time	Method
Pain score 1, 6, 12, 24 hours Numeric rating scale,Systemic concentration of bupivacaine 0, 15, 30, 60, 120, 240 min mcg/ml,Sensory loss 1, 6, 12, 24 hours after surgery Cold and pinprick sensation