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Clinical Trials/CTRI/2026/01/101175
CTRI/2026/01/101175Not yet recruitingNot Applicable

A Study on Comparison Between Paediatric Advanced Warning Score And Paediatric Early Warning Score In Predicting Intensive Care Unit Amissions In Infants And Children With Respiratory Distress

E Gokula Krishnan1 site in 1 country250 target enrollmentStarted: January 30, 2026Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
250
Locations
1

Study Overview

Brief Summary

This prospective observational study compares the effectiveness of the Paediatric Advanced Warning Score (PAWS) and the Paediatric Early Warning Score (PEWS) in predicting Paediatric Intensive Care Unit (PICU) admissions among infants and children presenting with respiratory distress. Conducted over a 1.5Year period (2025–2027) at the Emergency Department and PICU of VMKVMCH, Salem, the study includes 250 children aged 1 month to 12 years.

Both PAWS and PEWS are applied within 15 minutes of presentation using structured clinical parameters. The primary outcome is PICU admission, and the predictive performance of both scores is evaluated using sensitivity, specificity, positive and negative predictive values, and ROC curve analysis. Statistical analysis will be performed using SPSS software.

The study aims to determine whether PAWS, which incorporates additional physiological parameters such as oxygen saturation, temperature, and AVPU scale, offers superior predictive accuracy compared to PEWS. The findings are expected to guide clinicians in early identification of critically ill children with respiratory distress and support the adoption of a more effective early warning system in pediatric emergency care

Study Design

Study Type
Observational

Eligibility Criteria

Ages
1.00 Month(s) to 12.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Presenting with clinical signs of respiratory distress(e.g:tachypnea,chest retractions,nasal flaring,grunting,use of accessory muscle).

Exclusion Criteria

  • Children with pre-existing chronic respiratory conditions(e.g: cystic fibrosis,BPD) known CHD or NMD affecting respiration.

Investigators

Sponsor
E Gokula Krishnan
Sponsor Class
Research institution and hospital
Responsible Party
Principal Investigator
Principal Investigator

E Gokula Krishnan

Vinayaka Missions Kirupananada Variyar Medical College And Hospital

Study Sites (1)

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