Screening Tool for Malnutrition, Sarcopenia, and Cachexia

Completed

• Conditions: Cachexia; Sarcopenia; Malnutrition

• Registration Number: NCT06516367
• Lead Sponsor: Ain Shams University

Brief Summary

There is an accumulating evidence of the overlap and frequent co-occurrence of twasting conditions in older adults. Those conditions include malnutrition, sarcopenia, and cachexia, Therefore , a tool capable of simultaneously screening for all three conditions is imperative. In this study, we developed and validated a new tool for the simultaneous screening of muscle wasting diseases in older adults. The diagnostic accuracy of the new tool was compared to other validated screening tools including the Mini Nutritional Assessment-Short Form (MNA-SF), the Short Nutritional Assessment Questionnaire (SNAQ), and the Simple Questionnaire to Rapidly Diagnose Sarcopenia (SARC-F).

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-01
• Primary Completion: 2024-04-30
• Study Completion: 2024-04-30
• Status Verified: 2024-07
• Study First Submitted: 2024-07-03
• Study First Submitted QC: 2024-07-17
• Last Update Submitted: 2024-07-17
• Study First Posted: 2024-07-23
• Last Update Posted: 2024-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Participants Aged 65 years and older, who agree to participate

Exclusion Criteria

• Patients with critical illness.
• Patients with severe cognitive, hearing or visual impairment hindering proper communication
• Patients with physical disability that interfere with physical performance assessment or hand grip measurement
• Patient with any contraindication of to the use of BIA) e.g. presence of a pacemaker, other implanted electrical devices, or metal implants, volume overload

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
validity of a new tool for the simultaneous screening of muscle wasting diseases in older adults	10 months	Validity; Spearman's correlation coefficient was used to examine construct validity of the new tool
reliability of a new tool for the simultaneous screening of muscle wasting diseases in older adults	10 months	Relaibility; Cronbach's alpha coefficient was used to evaluate the internal consistency.

Secondary Outcome Measures

Name	Time	Method
The diagnostic accuracy of the new tool	10 months	The Receiver operating curve was plotted to detect the area under curve of the new tool, for diagnosing muscle wasting diseases.

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Egypt