Tourniquet effects on knee joint replacement

Not Applicable

Recruiting

• Conditions: The amount of cement penetration, the amount of bleeding after surgery, pain after surgery, the function of muscles around the knee after surgery, the amount of knee ROM after surgery, the relationship between BMD and cement penetration in TKA.; Osteoarthritis of knee

• Registration Number: IRCT20221116056519N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Diagnosis and confirmation of indications for total knee arthroplasty surgery
55 to 85 years old
BMI < 45
osteoarthritis with 3 score in kellgren and lawrence
ASA score 1 or 2
TKA with Nextgen Zimmer Biomet or DePuy prosthesis
primary TKA

Exclusion Criteria

previous knee fracture or surgery
malignancy
rheumatoid diseases
cardiovascular diseases
infectious diseases
neurologic diseases
hepatic failure disease
coagulopathy disorders
glucocorticoid or heparin or warfarin consumption
previous history of DVT or PTE
neuromuscular diseases

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparing the amount of cement penetration around the prosthesis in patients who undergo TKA surgery with and without the use of a tourniquet. Timepoint: 60 days after surgery, AP and LAT radiographs of the knee were taken, and based on the criteria of the Knee Society Radiographic Evaluation System, cement penetration was calculated in millimeters. Method of measurement: According to the Knee Society Radiographic Evaluation System in AP/Lat radiographs of the knee.

Secondary Outcome Measures

Name	Time	Method
Hemoglobin reduction rate after surgery. Timepoint: Hemoglobin level is measured before surgery and then on days 1, 7, 14, 60. Method of measurement: Based on cbc test and in gr/dl.;Body size changes. Timepoint: It is measured before surgery and then on days 1, 7, 14, 60. Method of measurement: In 2 places, 5 cm above the medial malleolus and 10 cm above the superior patella, the limb circumference is measured.;Knee range of motion. Timepoint: It is measured before surgery and then on days 1, 7, 14, 60. Method of measurement: in degrees and using goniometr.;Knee pain. Timepoint: It is measured before surgery and then on days 1, 7, 14, 60. Method of measurement: Based on the Visual Analogue Scale.;Strength of knee extensor and flexor muscles. Timepoint: It is measured before surgery and then on days 1, 7, 14, 60. Method of measurement: Clinical examination of muscle strength.;Post operation complications. Timepoint: Day 1,7,14,60. Method of measurement: Presence or absence of dvt/pte/bleeding/infection.