Proton Pump Inhibitors Use in Patients With Psoriasis
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 发起方
- 主要终点
- Efficacy - Change from baseline in skin lesions at 5 months
研究概览
简要总结
Proton pump inhibitors act in blocking acid secretion and also have antioxidant and anti-inflammatory properties. For that mechanisms possibly PPIs may have an anti-inflammatory action with improvement in skin lesions in patients with psoriasis.
详细描述
Proton pump inhibitors act in blocking acid secretion and also have antioxidant and anti-inflammatory properties. For that mechanisms possibly PPIs may have an anti-inflammatory action with improvement in skin lesions in patients with psoriasis.
The study will assess the evolution of skin lesions in psoriasis patients using PPIs
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnostic of Psoriasis
排除标准
- •Pregnancy
研究组 & 干预措施
Group A
Proton Pump Inhibitor esomeprazole 40 mg twice a day
干预措施: esomeprazole (Drug)
Group B
desonide
干预措施: desonide (Drug)
结局指标
主要结局
Efficacy - Change from baseline in skin lesions at 5 months
时间窗: Baseline - 5 months
Number of Participants With Treatment-Related Clinical Improvement of lesions Change From Baseline in skin lesions at 5 months
次要结局
未报告次要终点