临床试验/NCT01224509

NCT01224509终止不适用

Cervical Prostaglandin EP3 Receptor mRNA Expression 48 Hours After Administration of Mifepristone

University of Southern California1 个研究点分布在 1 个国家目标入组 18 人开始时间: 2004年9月最近更新: 2010年10月20日

适应症

干预措施

试验速览

阶段: 不适用
状态: 终止
发起方: University of Southern California
入组人数: 18
试验地点: 1
主要终点: The amount of expression of EP3 receptor mRNA levels in cervical tissue after the administration of mifepristone

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to determine the effect of mifepristone on the expression of three cervical EP3 receptor isoforms (EP3-2, EP3-3 and EP3-6) in pregnant women ≤63 days gestational age.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Basic Science
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: Female
接受健康志愿者: 否

入选标准

•good general health
•≥18 years old
•seeking termination of a viable intrauterine pregnancy of ≤63 days, without any evidence of a threatened or spontaneous abortion

排除标准

•medical problems
•confirmed or suspected ectopic pregnancy
•having taken medications in the seven days prior to enrollment that would affect PG synthesis or metabolism of mifepristone

研究组 & 干预措施

Mifepristone

Experimental

干预措施: Mifepristone (Drug)

Non-treatment

Active Comparator

干预措施: Non-treatment (Other)

结局指标

主要结局

The amount of expression of EP3 receptor mRNA levels in cervical tissue after the administration of mifepristone

时间窗: 48 hours after the administration of mifepristone

次要结局

The degree of cervical dilation after the administration of mifepristone(48 hours after the administration of mifepristone)

研究者

发起方

University of Southern California

申办方类型

Other

研究点 (1)

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