Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation
Recruiting
- Conditions
- Limbus Corneae
- Registration Number
- NCT02886611
- Lead Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
- Brief Summary
The study aims at searching for a genotype-phenotype correlation in patients with a genetic pathology of the ocular surface, in order to identify genetic abnormalities associated with the most severe clinical situations.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- genetic pathology of ocular surface
Exclusion Criteria
- Agonal glaucoma
- Low vision mostly related to retinal pathology
- Pregnant or breast feeding patient
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Genotype-phenotype Correlation baseline
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
Which genetic mutations in limbal stem cell deficiency correlate with severe ocular surface disease phenotypes in NCT02886611?
How does genetic profiling in NCT02886611 influence treatment outcomes compared to standard limbal stem cell transplantation?
What predictive biomarkers identify high-risk patients for ocular surface regeneration failure in genetic limbal stem cell deficiency?
What adverse events are observed in NCT02886611 for patients with specific genetic mutations causing limbal stem cell deficiency?
Are there gene therapy approaches or molecular targets being explored as alternatives to current limbal stem cell deficiency treatments in NCT02886611?
Trial Locations
- Locations (1)
Fondation Ophtalmologique Adolphe de Rothschild
🇫🇷Paris, France