Analysis of Influencing Factors for the Development of PTSD in Emergency Department Trauma Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 250
- 主要终点
- PTSD Incidence as Assessed by the PTSD Checklist for DSM-5 (PCL-5)
研究概览
简要总结
The goal of this observational study is to learn about the long-term effects of key factors such as cognitive flexibility, social support, and physiological stress on the occurrence of Post-Traumatic Stress Disorder (PTSD) in adult trauma patients treated in the emergency department. The main question it aims to answer is:
Among emergency department patients who have experienced major trauma, can factors such as early post-trauma cognitive flexibility, level of social support, inflammatory markers, and trauma severity predict the development of PTSD within 6 months? Participants will complete a series of online questionnaires and clinical assessments at baseline, 1 month, 3 months, and 6 months after the traumatic event.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 65 years old (inclusive);
- •Experienced a life-threatening major traumatic event, clearly diagnosed by a clinician;
- •The patient is able to communicate normally with medical staff through language;
- •The subject is fully informed and voluntarily signs the informed consent form.
排除标准
- •History of psychiatric disorders or current use of psychotropic medications;
- •Pre-existing cognitive impairment (e.g., dementia, Alzheimer's disease);
- •Terminal illnesses (such as advanced malignant tumors, end-stage organ failure, advanced neurological diseases, or any other condition judged by the attending physician to have a life expectancy of less than 6 months);
- •Inability to cooperate with follow-up.
结局指标
主要结局
PTSD Incidence as Assessed by the PTSD Checklist for DSM-5 (PCL-5)
时间窗: 6 months post-trauma
Number of participants with a total score ≥33 on the PCL-5 (range 0-80, higher scores indicate more severe PTSD symptoms) at 6 months after the traumatic event, indicating probable post-traumatic stress disorder (PTSD).
次要结局
- Association of Sociodemographic, Trauma-Related, and Psychosocial Factors with PTSD Status(Baselin and 6 months post-trauma)
研究者
wei zhao
Associate Professor
The First Affiliated Hospital of Air Force Medicial University