MedPath

Composix Kugel Mesh Recall Leaves Unresolved Problems of Patient Management

Suspended
Conditions
Incisional Hernia
Registration Number
NCT01520168
Lead Sponsor
University of Wuerzburg
Brief Summary

From its introduction in 2000 until its US recall in December 2005, the Composix Kugel Mesh was implanted in an estimated 350,000 patients worldwide.

The purpose of the study is to evaluate retrospectively the complications related to this mesh that occurred in our patients between 2003 and 2005, since new complications continue to be diagnosed, although the investigators discontinued the use of the mesh.

Detailed Description

From 2003 to 2005(2006) we implanted Komposix Kugel Meshes in 21 Patients with incisional ventral hernias. With the recall of January 2006 (in Germany), we stopped the implantation of this mesh and continued to monitor the patients with follow up and phone interviews. Late complications still continue to occur, mainly as a consequence of the product defect identified 7 years ago.

Recruitment & Eligibility

Status
SUSPENDED
Sex
All
Target Recruitment
21
Inclusion Criteria
  • Age > 18
  • Incisional hernia
Exclusion Criteria
  • Younger than 18 years
  • Peritonitis
  • Intestinal fistula

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Early postoperative complications6 months postoperative

Assessment of postoperative complications (wound complication, mesh infection, seroma)

Secondary Outcome Measures
NameTimeMethod
Long-term postoperative complications6 months to 5 years

Chronic pain, chronic and recurrent mesh infection, mesh bulging, incisional hernia and intestinal fistula

Trial Locations

Locations (1)

Department of General, Visceral, Vascular and Pediatric Surgery

🇩🇪

Wurzburg, Bavaria, Germany

© Copyright 2025. All Rights Reserved by MedPath