NL-OMON43161已完成不适用
Carnitine status in fit and pre-frail/frail elderly compared to healthy young individuals - Fitaal
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 78
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Healthy young subjects (n <= 26):
- •* 20 * 30 years of age
- •* BMI of 20 * 25 kg/m2;Healthy fit elderly subjects (n <= 26):
- •* * 75 years of age
- •* Fried score <= 0 ;Pre-frail/frail elderly (n<=26):
- •* * 75 years of age
- •* Fried score * 1*;Male/female ratio of the different groups will be matched.
排除标准
- •- Contra-indication for DEXA-scan, e.g. metal splinters
- •- Contra-indication for muscle biopsy, e.g. use of anticoagulants.
- •- a significant medical or surgical event or hospitalization within the previous three months
- •- currently or the last three months treated by a medical specialist
- •- diagnosed with cardiac failure, COPD or anaemia
- •- diagnosed dementia and not having access to a daily caregiver and not able to make their own trade-off, which will be assessed at our discretion. The potential subjects have to be able to reproduce what is said;
- •- diagnosed with cancer or receiving cancer treatment
- •- not able to understand the Dutch language
- •- Diagnosed neuromuscular disorders
- •- taking carnitine supplements
- •- current participation in other research
- •- usage of the following medications:
- •o Systemic corticosteroids
- •o Valproic acid
- •o Zidovudine;Additional exclusion criteria for the young individuals:
- •- Pregnant and nursing women
- •- Diabetes Mellitus type I and II
- •- Limited amount of performing sports, not more than 5 times a week
研究者
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