Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study

Not Applicable

Recruiting

• Conditions: Renal Cell Carcinoma
• Interventions: Procedure: preoperative remifentanil consumption; Procedure: postopeartive controlled anlagesia with morphine

• Registration Number: NCT05810571
• Lead Sponsor: Kocaeli University

Brief Summary

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continuous remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Detailed Description

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continious remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Study Timeline

• Study First Submitted: 2023-03-31
• Study First Submitted QC: 2023-03-31
• Study First Posted: 2023-04-12
• Status Verified: 2024-09
• Study Start: 2024-10-24
• Last Update Submitted: 2024-10-24
• Last Update Posted: 2024-10-26
• Primary Completion: 2027-01-03
• Study Completion: 2027-01-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• ASA 1-3
• open nephrectomy elective patients
• BMI<35

Exclusion Criteria

• ASA 4-5-6
• Laparoscopic nephrectomy
• infection at the block side
• coagulation disorder
• BMI>35

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
erector spina plane block	preoperative remifentanil consumption	this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine
quadratus lumborum block	preoperative remifentanil consumption	this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine
erector spina plane block	postopeartive controlled anlagesia with morphine	this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine
patient controlled analgesia	preoperative remifentanil consumption	this group of patients received no block, received only postoperative patient-controlled analgesia with morphine
patient controlled analgesia	postopeartive controlled anlagesia with morphine	this group of patients received no block, received only postoperative patient-controlled analgesia with morphine
quadratus lumborum block	postopeartive controlled anlagesia with morphine	this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine

Primary Outcome Measures

Name	Time	Method
postoperative morphine consumption	24 hour postoperatively	amount of postoperative morphine use of the patient's

Secondary Outcome Measures

Name	Time	Method
numeric rating scale	24 hour postoperatively	numeric rating scores of the patient's postoepartively
peroperative remifentanil consumptions	4 hour preoperatively	amount of remifentanil use of the patient's

Trial Locations

Locations (1)

Kocaeli University Medical Faculty; 🇹🇷 Kocaeli, Turkey