Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study

Not Applicable

Recruiting

• Conditions: Renal Cell Carcinoma

• Registration Number: NCT05810571
• Lead Sponsor: Kocaeli University

Brief Summary

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continuous remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Detailed Description

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continious remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Study Timeline

• Study First Submitted: 2023-03-31
• Study First Submitted QC: 2023-03-31
• Study First Posted: 2023-04-12
• Status Verified: 2024-09
• Study Start: 2024-10-24
• Last Update Submitted: 2024-10-24
• Last Update Posted: 2024-10-26
• Primary Completion: 2027-01-03
• Study Completion: 2027-01-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• ASA 1-3
• open nephrectomy elective patients
• BMI<35

Exclusion Criteria

• ASA 4-5-6
• Laparoscopic nephrectomy
• infection at the block side
• coagulation disorder
• BMI>35

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
postoperative morphine consumption	24 hour postoperatively	amount of postoperative morphine use of the patient's

Secondary Outcome Measures

Name	Time	Method
peroperative remifentanil consumptions	4 hour preoperatively	amount of remifentanil use of the patient's
numeric rating scale	24 hour postoperatively	numeric rating scores of the patient's postoepartively

Trial Locations

Locations (1)

Kocaeli University Medical Faculty; 🇹🇷 Kocaeli, Turkey