Effects of Chronic Intake of High in Flavonols Cocoa on Body Composition, Adipokines and Exercise Performance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Change of body fat mass at 10 weeks
研究概览
简要总结
The decrease in body fat percentage improves exercise performance, reducing race time. The intake of cocoa improves the body fat composition in obese and diabetic people by improving their cardiovascular disease risk factors. Although epidemiological studies indicate that healthy subjects who consume cocoa have lower body fat composition, there is no study indicating whether cocoa improves fat composition in athletes. The aim of the study was to determine if the intake of cocoa rich in flavonoids improves the fat composition of athletes, modifying the systemic levels of adipokines (folistatin, myostatin and leptin), resulting in an improvement of physical performance.
详细描述
The objective of this project was to investigate the effects of chronic daily consumption of high in flavanols cocoa in body composition and performance of endurance athletes:
A randomized, blinded, parallel placebo controlled intervention study was carried out in endurance athletes . The number of male athletes enrolled in the study was 40, with ages between 18 and 50 years and an aerobic power consumption of oxygen greater than or equal to 55 mL / kg / min). The intervention was carried out for 10 weeks. Cocoa or placebo (maltodextrin) were supplied in sachets of a single daily dose. Cocoa provided 425 mg of flavanols/ day.
Athlete's body composition was evaluated by dual-energy X-ray absorptiometry (DEXA). Exercise performance was evaluated with a treadmill test protocol determining the maximum aerobic capacity and also by determining the time necessary to run a kilometer at maximum speed.
Adipokines (follistatin, myostatin and leptin) in plasma and serum samples were determined by ELISA.
Diet was determined by three 24h-recall questionnaries and a Food Frecuency questionnaire.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Investigator, Outcomes Assessor)
盲法说明
Cocoa and maltodextrin (placebo) are provided in identical sachets which are identified with the letters A and B respectively.
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age between 18 and 50 years
- •Aerobic power of oxygen consumption greater than or equal to 55 mL / kg / min
排除标准
- •Intake of chronical medication.
- •Intake any type of nutritional or ergogenic supplements.
- •Vegetarian or vegan diet
- •Any diagnosed disease at the time of inclusion or during the study
研究组 & 干预措施
Cocoa group
The cocoa was provided in 5 g sachets. The intervention last 10 weeks. Cocoa was provided in a single daily dose of 5 g, which provided 425 mg of flavonoids
干预措施: Cocoa group (Dietary Supplement)
Placebo group
Maltodextrin (5 g) was supplied as placebo in sachets identical to those provided for cocoa.
干预措施: Placebo group (Dietary Supplement)
结局指标
主要结局
Change of body fat mass at 10 weeks
时间窗: Fat mass was analyzed at the beginning (baseline time = 0) and after 10 weeks of intervention
Energy X-ray absorptiometry (DEXA).
次要结局
- Change in Sport performance test at 10 weeks(Sport performance was analyzed at the beginning (baseline time) and after 10 weeks of intervention)
- Change from baseline of leptin(Leptin was analyzed at the beginning and at the end of the 10-week intervention.)
- Change in Dietary habits at 10 weeks(Diet was analyzed at the beginning (baseline dose) and after 10 weeks of intervention.)
- Change of lean mass at 10 weeks(Lean mass was analyzed at the beginning (baseline time) and after 10 weeks of intervention)
- Change in Sport performance test 2 at 10 weeks(Sport performance was analyzed at the beginning (baseline time and after 10 weeks of intervention)
- Change from baseline of adipokines at 10 weeks(Myostatin and Follistatin were analyzed at the beginning and at the end of the 10-week intervention.)
- Change in Dietary habits 2 at 10 weeks(Diet was analyzed at the beginning (baseline dose) and after 10 weeks of intervention.)
研究者
Mar Larrosa
Tenure Professor
Universidad Europea de Madrid