Emotions Recognition in Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Lille Catholic University
- Enrollment
- 101
- Locations
- 1
- Primary Endpoint
- Emotion's intensity
- Status
- Completed
- Last Updated
- 4 months ago
Overview
Brief Summary
Through this study, a group composed of multiple sclerosis patients will be compared to a healthy volunteers group to determine if the positive emotions recognitions is preserved in the first group.
Detailed Description
Different studies have highlighted the specific deficiency concerning emotions recognition in multiple sclerosis. Patients with multiple sclerosis are reported to have more difficulty recognising negative emotions, especially anger and fear. In this context, RECODE study has a twofold objective: * To determine whether the positive emotions recognition remains preserved by combining behavioural and neurophysiological measures (electrodermal activity). * To study this disorder's etiology through a comparison between a multiple sclerosis patient group and a control group (matched in sex, age, and education's level).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male or female between 18 and 55 years old.
- •Understand and able to express themselves in French.
- •EXPERIMENTAL GROUP :
- •Relapsing-remitting form (RRMS)
- •With an EDSS \< 4 (Expanded Disability Status Scale)
- •No significant motor, cerebellar or somatosensory disorders of the upper limbs or visual disorders (EDSS specific parameter \<2)
- •No flare-up in the last 6 weeks
- •No corticosteroids taken in the last 4 weeks
- •CONTROL GROUP :
- •Lack of global cognitive deterioration (according to Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) standards).
Exclusion Criteria
- •Persons with previous neurological pathologies, head trauma with loss of consciousness, psychiatric pathologies, serious general affections, perceptive or dysarthric disorders preventing verbal communication or reading,
- •People with sensory disorders (visual and auditory) that interfere with the performance of neuropsychological tests;
- •Treatment with psychotropic drugs (except benzodiazepines and hypnotics).
- •Refusal to participate after clear and fair information about the study.
- •Major persons under guardianship, under judicial protection, persons deprived of liberty.
- •Pregnant or breastfeeding women
Outcomes
Primary Outcomes
Emotion's intensity
Time Frame: Day 0
Through the emotion recognition test, the attendees will have to evaluate the emotion's intensity conveyed by the stimuli on a scale ranging from 1 (the emotion conveyed is not very intense) to 10 (the emotion conveyed is very intense).
Emotion's valence
Time Frame: Day 0
Through the emotion recognition test, the attendees will have to evaluate the emotion's valence conveyed by the stimuli on a scale ranging from 1 (the emotion conveyed is negative) to 10 (the emotion conveyed is positive).
Emotion recognition
Time Frame: Day 0
Comparison of the answers obtained to the recognition question "In your opinion what is the emotion conveyed by this extract/face" in both groupsThrough the emotion recognition test, the attendees will have to evaluate the emotion perceived among 6 basic emotions (anger, disgust, joy, fear, surprise, sadness) and 14 complex emotions (benevolence, disappointment, boredom, enthusiasm, mischief, pride, frustration, shame, hostility, worry, interest, jealousy, sorrow, sneakiness).
Certainty's degree of answers
Time Frame: Day 0
Certainty's degree of the attendees answers to the recognition question on a scale from 1 ("I am not at all certain of my answer") to 10 ("I am quite certain of my answer")
Secondary Outcomes
- California Verbal Learning Test (CVLT)(Day 0)
- Brief Visuo-spatial Memory Test (BVMT)(Day 0)
- Trail Making test(Day 0)
- State Trait Anxiety Inventory Y-B (STAI Y-B)(Day 0)
- Beck Depression Inventory (BDI)(At the unique experimental session)
- Dot Probe Task(Day 0)
- Change in the electrodermal response during emotion recognition test(Day 0)
- Stroop test(Day 0)
- Symbol Digit Modalities Test (SDMT)(Day 0)
- Verbal fluency test(Dat 0)
- State Trait Anxiety Inventory Y-A (STAI Y-A)(Day 0)
- Toronto Alexithymia Scale-20 (TAS-20)(Day 0)