Rapid test for rheumatoid arthritis
Not Applicable
Completed
- Conditions
- Health Condition 1: M059- Rheumatoid arthritis with rheumatoid factor, unspecified
- Registration Number
- CTRI/2020/10/028596
- Lead Sponsor
- Diabetes Research Society
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
1. 18 years or older, male and female
2. Subjects confirmed, suspected or with symptoms of Rheumatoid Arthritis
3. Smoking or non-smoking
4. Subjects willing for participating in the study and providing informed consent
Exclusion Criteria
1. Subjects unwilling to participate
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The expected Outcomes are: <br/ ><br>1. Significant positive correlation between presence or absence of (blood and salivary) IgG antibodies (against citrullinated albumin) and, severity and duration of disease after onset of symptoms. <br/ ><br>2. Positive association in individuals who have specific disease (RA with elevated ACCP/ACPA or RF) and then antibodies remain detrimental for the remainder of the disease period, warranting more frequent and regular monitoring for anti-cit Alb antibodies.Timepoint: first visit only, <br/ ><br>cross-sectional study
- Secondary Outcome Measures
Name Time Method The expected secondary study outcomes are: <br/ ><br>1. Direct relation between presence of antibodies in blood and oral fluid. <br/ ><br>2. IgG antibodies in blood are comparably expressed and demonstrated in oral fluid (GCF)Timepoint: first visit only, <br/ ><br>cross-sectional study