MedPath

Comparison of total intravenous anesthesia(TIVA) with propofol and inhalation anesthesia with isoflurane in patients undergoing posterior lumbar fusion surgery

Not Applicable
Recruiting
Conditions
Condition 1: Lumbar spinal stenosis. Condition 2: complications of total intravenous anaesthesia. Condition 3: complications of inhalation anesthesia.
Spinal stenosis, lumbosacral region
Other complications of anesthesia
T88.5
M48.07
Registration Number
IRCT20230208057358N2
Lead Sponsor
Hamedan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
66
Inclusion Criteria

Candidate patients for posterior fusion surgery of lumbar vertebrae with pedicle screw fixation method
Patients who will have only 3 to 5 levels of lumbar spine fusion
Willingness and consent to participate in the study
Age between 18 and 65 years
American Society of Anesthesiologists (ASA) Class I-II physical status
Body mass index (BMI) less than 35 kg/m2

Exclusion Criteria

Trauma patients
Allergy to anesthetics used in the study
Patients with severe chronic diseases (cardiovascular, respiratory, nervous, liver, kidney, electrolyte disorders)
patient with uncontrolled blood pressure
History of drug use
Patients who receive medication or liquid therapy outside of routine before, during and after surgery
History of bleeding disorders and treatment with anticoagulants
Excessive bleeding (more than MABL)
Women if they are menstruating
Abnormal coagulation profile (platelet count less than 50x103/µL, PTT greater than 50 seconds, or INR greater than 1.3 on preoperative testing)
Patients with a history of frequent nausea and vomiting and taking antiemetics in the 24 hours before surgery
Patients with mental disorders and mental retardation, dementia or schizophrenia
Recent brain surgery or cerebrovascular accidents

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.