Effect of toothpaste containing fennel extract on the oral environment of patients with periodontal disease
Not Applicable
- Conditions
- Periodontal disease
- Registration Number
- JPRN-UMIN000052974
- Lead Sponsor
- ihon University School of Dentistry at Matsudo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients who are pregnant or may be pregnant 2. Patients with uncontrolled diabetes, severe heart disease, renal dysfunction, hepatic dysfunction, etc. for which the dentist in charge deems inappropriate. 3. Patients who are taking antibody drugs or anti-inflammatory drugs for autoimmune diseases, etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of total bacteria and periodontal pathobionts in saliva and gingival crevicular fluid
- Secondary Outcome Measures
Name Time Method 1. Microbiota in saliva and gingival crevicular fluid 2. Probing pocket depth (PPD) 3. Clinical attachment loss (CAL) 4. Tooth mobility 5. Bleeding on probing (BOP) 6. Gingival index (GI) 7. Plaque index (PlI) 8. Plaque control record (PCR) 9. Periodontal epithelial surface area (PESA) 10. Periodontal inflamed surface area (PISA) 11. X-ray examination