Exploration on the Efficacy of Different Anesthesia Methods in Transbronchial Biopsy
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Anesthesia
- Sponsor
- Sichuan Provincial People's Hospital
- Enrollment
- 800
- Locations
- 1
- Primary Endpoint
- Diagnostic efficacy
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
This study investigates the efficacy of different anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy using an electronic bronchoscope. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method, operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status.
Detailed Description
General anesthesia and local anesthesia are the primary anesthesia methods for interventional respiratory endoscopy. While general anesthesia offers greater comfort, it carries anesthesia-related risks. Local anesthesia, on the other hand, provides a relatively low surgical risk and cost-effectiveness. However, there is limited research on whether its diagnostic value is inferior to that of general anesthesia.This study investigates the efficacy of the two anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method(forcep/cryobiopsy), operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status(pneumothorax、hemorrhage).
Investigators
Guanghong Zhou
Department of Respiratory and Critical Care Medicine
Sichuan Provincial People's Hospital
Eligibility Criteria
Inclusion Criteria
- •Completed Transbronchial Biopsy；the platelets count and PT, APTT tests were normal, normal ECG, Anesthesiologist evaluation was needed in General anesthesia group.
Exclusion Criteria
- •patients with contraindication of bronchoscopy (such as respiratory failure and acute cardio-cerebrovascular events), and women who were pregnant.
Outcomes
Primary Outcomes
Diagnostic efficacy
Time Frame: baseline
The diagnostic positivity rate(%) of transbronchial biopsy under different anesthesia methods between two groups
Secondary Outcomes
- Clinical information(baseline)
- lesion location (left/right/other)(baseline)
- lesion size (mm)(baseline)
- Postoperative complications (hemorrhage or pneumothorax）(baseline)
- Operation time(intraoperative)