The Evaluation of OLGA and OLGIM Stage Systems for Prediction of Gastric Cancer Risk and Interaction With Other Risk Factors According to Lauren's Classification
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,900
- 试验地点
- 1
- 主要终点
- The evaluation of OLGA and OLGIM stage systems with serum pepsinogen for prediction of gastric cancer risk
研究概览
简要总结
To validate OLGA and OLGIM staging system with serum pepsinogen for estimating GC risk according to Lauren's histologic classification in South Korea. Also attempted to estimate synergistic interaction among the several risk factors to help establish surveillance strategy.
详细描述
To validated the OLGA and OLGIM staging system with serum pepsinogen to estimate gastric cancer risk according to Lauren's histologic classification in South Korea, where the incidence rate of GC is high. In addition, the investigators attempted to investigate the interaction among the several risk factors including OLGA or OLGIM staging system for the risk of GC to help establish surveillance strategy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Control group
- •those who were between 25 and 80 years old and did not have any evidence of gastric cancer and gastric dysplasia, esophageal tumor and MALToma in upper gastrointestinal endoscopy
- •Gastric cancer group
- •Patients diagnosed as gastric cancer in the upper gastrointestinal endoscopy at the time of participating in the study between 25 and 80 years old.
排除标准
- •history of previous gastrointestinal surgery,
- •any other malignancy
- •cardia cancer
- •who do not perform endoscopic biopsy
- •pathologically proven gastric dysplasia
结局指标
主要结局
The evaluation of OLGA and OLGIM stage systems with serum pepsinogen for prediction of gastric cancer risk
时间窗: per 1 year
To validate OLGA and OLGIM staging system with serum pepsinogen for estimating GC risk according to Lauren's histologic classification
次要结局
未报告次要终点
研究者
Nayoung Kim
Professor
Seoul National University Bundang Hospital