The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Time to awakening
研究概览
简要总结
The good quality of recovery after general anesthesia is one of goals for short procedures and ambulatory surgeries. The study's objective was to compare the quality of recovery after general anesthesia with desflurane and sevoflurane with laryngeal mask airway for endoscopic ureteral lithotripsy.
详细描述
This is a randomized controlled trial. There were 60 cases of endoscopic ureteral lithotripsy under general anesthesia with laryngeal mask airway were enrolled. All cases were randomly divided into two group (desflurane or sevoflurane). Each group had 30 cases. Primary outcome was time to awakening. Secondary outcomes were time to wash-out of volatile anesthetics, time to extubation, irritation after awakening, and modified Aldrete score.
Statistical analysis was performed by using Kaplan-Meieir curve and log-rank test for time to adequate depth of anesthesia and time to awakening; t-test for time to wash-out of volatile anesthetics; chi-square test for depth of anesthesia by PRST score, irritation after awakening and Aldrete score; Fisher test for adverse effects of volatile anesthetics.
The research was approved by Gia Dinh People Hospital ethics committee
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All eligible subjects who underwent endoscopic ureteral lithotripsy under general anesthesia
- •ASA I and II
排除标准
- •Contraindication to laryngeal mask airway.
- •Indication for conversion to tracheal intubation during surgery.
- •History of malignant hyperthermia.
- •Pregnancy.
- •Obese (BMI >25 kg/m2).
- •Substances abuse.
结局指标
主要结局
Time to awakening
时间窗: After stopping volatile anesthetics to patient awakening, up to 30 minutes.
Time required for awakening
次要结局
- Time to wash-out of volatile anesthetics(After stopping volatile anesthetics to complete wash-out of volatile anesthetics, up to 30 minutes)
- Time to extubation(After stopping volatile anesthetics to readiness for extubation, up to 30 minutes)
- Irritation after awakening(After awakening to eligible discharge, up to 2 hours.)
- Adverse effects of volatile anesthetics(After providing volatile anesthetics until they were stopped, up to 90 minutes)