Correlation Between the 'Nine Holes Peg Test' Performance and the Triple Stimulation Technique Within a Group a Patients With Multiple Sclerosis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Brugmann University Hospital
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Amplitude ratio of the TST
Study Overview
Brief Summary
The main goal of this study is to determine if the Triple Stimulation Technique (TST) can be correlated to performance in the manual dexterity 'nine holes peg' test, within a control group and a group of patients with multiple sclerosis.
TST (Triple stimulation technique) combines two techniques used in neurologic diagnosis: magnetic stimulation and electroneuromyography. It is based on the principle of two collisions between the descending central stimulation (magnetic stimulation) and the ascending peripheric stimulation. TST allows to better quantify central nervous system diseases. The abnormal amplitude registered by TST is proportional to the intensity of conduction disorders. The evaluation of these disorders is more precise than with the magnetic stimulation technique alone.
The Nine Hole Pegs technique is a simple manual dexterity test, commonly used in ergotherapy. The participant tries to place 9 pegs in a 9 holes perforated plate, and then tries to remove them as quickly as possible. The hand must stay in a depression within the plate, thereby insuring a constant distance between the hand and the pegs.
The nine hole peg will be realized first, and the triple stimulation examination performed after. The acquired data will be analyzed in order to find a correlation between the impairment level given by these two tests.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 20 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Control group:
- •No history of neurological disease
- •No medicines intake that could disturb performance within the tests (psychotropic medications, sedatives, anti spastic and drugs acting on neuromuscular transmission).
- •Multiple sclerosis group
- •Multiple sclerosis diagnose. Patients followed by Dr Dachy, within the CHU Brugmann Hospital.
Exclusion Criteria
- •Persons carrying ferromagnetic material (implants, pacemaker).
- •Epilepsy history.
- •Patients who have had a head trauma with loss of consciousness and/or brain injury.
- •Pregnant woman.
Arms & Interventions
Multiple sclerosis
Patients with multiple sclerosis, followed by Dr Dachy within the CHU Brugmann Hospital.
Intervention: Nine Hole Test (Other)
Multiple sclerosis
Patients with multiple sclerosis, followed by Dr Dachy within the CHU Brugmann Hospital.
Intervention: Triple Stimulation Technique (Device)
Control group
Control group without neurological pathology
Intervention: Nine Hole Test (Other)
Control group
Control group without neurological pathology
Intervention: Triple Stimulation Technique (Device)
Outcomes
Primary Outcomes
Amplitude ratio of the TST
Time Frame: during the TST (30 min)
Amplitude of the motor evoked potentials
Time Frame: during the TST (30 min)
Surface ratio of the TST
Time Frame: during the TST (30 min)
Nine Holes Peg test result
Time Frame: Baseline
Secondary Outcomes
No secondary outcomes reported
Investigators
Bernard Dachy
Head of clinic
Brugmann University Hospital