CogLife 2.0
- Conditions
- F00F01F02F03F06.7Dementia in Alzheimer diseaseVascular dementiaDementia in other diseases classified elsewhereUnspecified dementiaMild cognitive disorder
- Registration Number
- DRKS00030000
- Lead Sponsor
- niklinik Köln - Zentrum für Innere Medizin II, Schwerpunkt klinische Altersforschung
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 125
1) Subject is 65 years or older
2) Subject is showing a subjective cognitive impairment OR subject is showing no cognitive impairment OR subject is showing a mild cognitive impairment
3) Subject is capable to give an informed consent regarding the participation in the study or has a legal representative
4) Subject is not suffering from a life threatening disease
5) Subject shows an CIRS-G-Score (Cumulative Illness Rating Scale-Geriatric) = 2
6) Subjects is not suffering from a neurological or psychiatric disease
7) Subject has an BMI between 18 and 30
8) Subject does not take any vitamin supplements
9) Subject is not vegetarian or vegan
10) Subject does not take any antioxidants
1) Subject does not meet the inclusion criteria
2) Subject is not able to take part in the questioning due to barrier of language
3) Current substance abuse
4) Subject is suffering from a life threatening disease
5) Missing or not undertaken consent to take part in this study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of the impact of metabolism products (metabolome, especially lipidoma) and the plasma lipid level on the cognitive functions of elderly subjects.
- Secondary Outcome Measures
Name Time Method 1) Evaluation of the MPI<br>2) Comparison of the undertaken tests<br>A) cognitive performence tests<br>B) metabolism products (metabolome, especially lipidoma) and plasma lipid level<br>3) Evaluation of physical fitness<br>1-year Follow-Up planned