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Immunogenicity of COVID-19 vaccines in KCMH health care workers

Conditions
COVID-19
Registration Number
TCTR20210325003
Lead Sponsor
Ratchadapiseksompotch Research Fund
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
1
Inclusion Criteria

1.The subject is aged > 18 years
2.Subjects had no history of COVID-19 vaccination before enrollment
3.Subjects who can comply with trial procedures and are available for the duration of follow-up

Exclusion Criteria

1.Subjects who received any other vaccines within 1 month prior to enrollment
2.Subjects who received blood or blood product or immunoglobulin within 3 months prior to enrollment
3.Subjects participating in any clinical trial with COVID-19 immunogenicity

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Seroconversion rate by neutralizing antibody 4 weeks, 6 and 12 months after complete immunization cPass SARS-CoV-2 Neutralization Antibody Detection Kit GenScript
Secondary Outcome Measures
NameTimeMethod
Seroconversion rate by IgG 4 weeks, 6 and 12 months after complete immunization Enzyme-Linked Immunosorbent Assay (ELISA) ,Immunogenicity to variant strain 4 weeks after complete immunization Plaque reduction neutralization test PRNT,Immunogenicity by T cell 4 weeks after complete immunization IFN gamma ELISPOT
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