跳至主要内容
临床试验/NCT04522700
NCT04522700尚未招募不适用

Reconstruction of Maxillary and Midfacial Defects Using Latissimus Dorsi Scapular Free Flaps

hassan harby mohamed2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2020年9月25日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
2
主要终点
reconstruction and restoration of facial contour.

研究概览

简要总结

Bony reconstruction of the midface with free tissue transfer is complex and challenging due to structural considerations such as the need for orbital support, patency of the nasal cavity, restoration of the palate and alveolus and skull base support when needed. As a result, bony reconstruction is important especially for patients who experience diplopia, hypoglobus and enophthalmos postoperatively.

Orocutaneous and nasocutaneous fistulae and infection due to communication with the oral cavity or sinuses are also common complication . Finally, cosmetic deformities from inadequate projection are also a concern.

Cosmetic and functional outcomes are improved with bony reconstruction as it is able to provide rigid support of key structures, restoration of contour, affords the possibility of dental rehabilitation and is less likely to contract significantly following radiation treatment.

Subscapular system free flaps (SF) are uniquely suited to address the needs of midface reconstruction. A substantial amount of bone can be harvested from the lateral scapular border and scapular tip, each with different shapes and thicknesses. Chimeric flaps can be harvested in various combinations, adding Para scapular and scapular skin paddles, latissimus muscle (with or without skin), serratus muscle and rib. Additionally, due to the vascular organization of this network, these components can be harvested off separate pedicles, offering great flexibility and freedom of movement relative to each other .

详细描述

reconstruction of defects post maxiilectomy by scapular free flaps

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
— 至 75 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients post maxillectomy due to benign maxillary lesions.
  • All patients post maxillectomy with malignant maxillary swelling with no distant metastases.
  • All patients which implants are needed after surgery for head and neck neoplasia .

排除标准

  • Oropharyngeal, Nasopharyngeal, and Hypopharyngeal cancers, and lip cancers;.
  • Recurrent tumors resulting in implant loss.
  • Previous free flap harvest from scapula.

结局指标

主要结局

reconstruction and restoration of facial contour.

时间窗: 6 month

reconstruction of the maxilla by provide rigid bony support post maxillectomy with measurement of graft taken and union occur by follow up with MSCT of the facial bone with 3D film .

次要结局

未报告次要终点

研究者

发起方
hassan harby mohamed
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

hassan harby mohamed

principal investigator

Assiut University

研究点 (2)

Loading locations...

相似试验