ChiCTR-TRC-12002135已完成4 期
Randomized Evaluative Study of Phenylephrine Or Norepinephrine for maintenance of blood pressure during spinal anaesthesia for caesarean Delivery: The RESPOND study
RGC GRF1 个研究点 分布在 1 个国家目标入组 104 人开始时间: 2012年7月1日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 104
- 试验地点
- 1
- 主要终点
- Cardiac output 5 min after spinal injection
研究概览
简要总结
Study of Phenylephrine Or Norepinephrine for maintenance of blood pressure during spinal anaesthesia for caesarean Delivery
研究设计
- 研究类型
- Interventional
- 主要目的
- 随机平行对照
入排标准
- 年龄范围
- 18 至 35（—）
- 性别
- Female
入选标准
- •American Society of Anesthesiologists Physical Status 1 or 2 normotensive non-labouring parturients with term singleton pregnancies who are scheduled for elective Caesarean section and who have been judged suitable and have agreed to have for spinal anaesthesia according to usual clinical criteria.
排除标准
- •Known fetal abnormality, preexisting or pregnancy-induced hypertension, known cardiovascular or cerebrovascular disease, thrombocytopaenia, coagulopathy, or any medical contraindication to spinal anaesthesia, weight <50 kg or >100 kg, height <140 cm or >180 cm, inability or refusal to give informed consent, age < 18 years, patients taking monoamine oxidase inhibitors or tricyclic antidepressants, patients with mesenteric or peripheral vascular thrombosis, patients with renal impairment.
研究组 & 干预措施
Two groups
Norepinephrine versus Phenylephrine 30 min approximately
结局指标
主要结局
Cardiac output 5 min after spinal injection
次要结局
- Haemodynamic control - intraoperatively
- Umbilical cord blood gases – after delivery
- Umbilical cord blood catecholamine concentrations – after delivery
研究者
研究点 (1)
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