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Clinical Trials/ACTRN12614000815662
ACTRN12614000815662
Withdrawn
未知

A prospective randomised double-blind, double-dummy, placebo-controlled crossover study on 15 healthy male participants to determine whether Glucagon-like peptide-1 (GLP-1) stimulates or suppresses pancreatic exocrine function in health.

Dr Adam Deane0 sites15 target enrollmentJuly 31, 2014

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Dr Adam Deane
Enrollment
15
Status
Withdrawn
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 31, 2014
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional
Sex
Male

Investigators

Sponsor
Dr Adam Deane

Eligibility Criteria

Inclusion Criteria

  • Healthy Male volunteers between the ages of 18\-35

Exclusion Criteria

  • Inability to give informed consent
  • History of diabetes
  • History of pancreatitis
  • Lipase level \>210 U/L
  • Amylase level \> 110 U/L
  • Estimated glomerular filtration rate \< 60ml/min
  • Impared liver function (ALT \>55 U/L; Albumin \<34g/l, ALP \>110 U/L; Bilirubin \>25 umol; GGT \> 80 U/L)
  • Haemoglobin \<135g/L
  • Body Mass Index \>32kg/m2
  • Smoking \> 10 cigarettes/day

Outcomes

Primary Outcomes

Not specified

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