EUCTR2005-000749-13-GB进行中（未招募）1 期
A Randomised Double-Blind Trial of Medical Treatment In Marfan Syndrome.
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •Entry criteria:
- •? Clinical diagnosis of Marfan syndrome (Ghent criteria)
- •? Aged 16-50 years; either gender
- •On no treatment for Marfan syndrome, or on beta-blocker or other
- •monotherapy only
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •? Previous aortic dissection or aortic surgery
- •? Severe aortic or mitral regurgitation; or cardiac disease unrelated
- •to Marfan Syndrome
- •? Pregnancy, or of child-bearing age if at risk of pregnancy
- •? Aortic diameter at sinotubular junction = 5.0 cm
- •? Contraindications to specific drug treatment: e.g. asthma
- •(?-blockers), or renal dysfunction defined as serum creatinine >150 µmol/l
- •(ACE inhibitor)
研究者
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