Effects of Femoral Nerve Mobilization on Pain Intensity, Function, Quality of Life and Central Sensitization in Patients With Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- pain intensity
研究概览
简要总结
Background: Knee osteoarthritis (KO) is considered as a cause of disability among the elderly, causing pain, reduced quality of life, and decreased functionality. There is a limited knowledge about using femoral nerve mobilization in treating patients with arthritic changes.
Objectives: This study will be designed to determine the efficacy of adding of femoral nerve mobilization on pain intensity, function, quality of life and central sensitization in patients with knee osteoarthritis Methods: Thirty patients (aged ≥50 years with KO Kellgren-Lawrence grades I-II) will be included in this study: Patients will randomly be assigned into two groups: group A will receive traditional physical therapy while group B will receive femoral nerve mobilization in addition to traditional physical therapy. Three sessions will be performed for four weeks by 3 session /week. Patients will be evaluated for pain intensity using the numerical rating scale (NRS), knee function by WOMAC scale, quality of life by 12-item Short Form Survey questionnaire (SF-12) and central sensitization by the Arabic version of central sensitization inventory (CSI).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients aged 50 years or older, diagnosed with KO according to theAmerican College of Rheumatology's criteria with knee pain, and grade I or II on the Kellgren-Lawrence radiographic scale
排除标准
- •individuals suffering from chronic conditions considered to be perpetuating factors (e.g., fibromyalgia)
- •those with conditions causing lower extremity pain
- •individuals who had taken analgesics within 24 h before evaluations
- •those who had undergone corticosteroid or local anesthetic infiltration in the year prior to the study or during the follow-up period
- •those using substances that could interfere with treatment
- •those with a previous diagnosis of neuropathy (lumbosacral plexus) or myopathy
- •those with contraindications to mobilization or exercise, and those with cognitive deficits (dementia, Alzheimer's).
研究组 & 干预措施
Control group
Traditional physical therapy
干预措施: traditional physical therapy (Other)
Neural mobilization group
traditional physical therapy plus femoral nerve mobilization
干预措施: traditional physical therapy (Other)
Neural mobilization group
traditional physical therapy plus femoral nerve mobilization
干预措施: Femoral nerve mobilization (Other)
结局指标
主要结局
pain intensity
时间窗: after 4 weeks
The pain was assessed by the numerical rating scale (NRS) where zero indicating no pain and 10 indicating maximal pain
central sensitization
时间窗: after 4 weeks
The CSI is a validated questionnaire designed to identify symptoms associated with central sensitization. It has two components: Scale A assesses 25 common symptoms in individuals with central sensitization, resulting in a score ranging from 0 to 100. This score was interpreted as follows: subclinical (0-29), mild (30-39), moderate (40-49), severe (50-59), and extreme (60-100). Scale B, which is not scored, collects information on previous diagnoses of specific diseases
次要结局
未报告次要终点
研究者
Mohammad Moustafa Aldosoukki Hegazy
assisstant professor , department of health and rehabilitation sciences, college of applied medical siences
Prince Sattam Bin Abdulaziz University