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Clinical Trials/NCT05888181
NCT05888181
Completed
N/A

Effectiveness and Feasibility of a Mobile Health Self-management Intervention for Patients With Rheumatoid Arthritis: the App-based Education and GOal-setting in Rheumatoid Arthritis Trial

Universitaire Ziekenhuizen KU Leuven2 sites in 1 country128 target enrollmentMarch 3, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Rheumatoid Arthritis
Sponsor
Universitaire Ziekenhuizen KU Leuven
Enrollment
128
Locations
2
Primary Endpoint
Arthritis Self-Efficacy Scale (ASES)
Status
Completed
Last Updated
11 months ago

Overview

Brief Summary

The purpose of this pragmatic, investigator-initiated, multicentre randomised controlled trial is to study the effectiveness and feasibility of a mobile app-based self-management intervention for patients with rheumatoid arthritis (RA), aiming to improve self-efficacy for the management of RA-related symptoms. The intervention consists of education, lifestyle advice and remote monitoring elements and is based on principles of goal setting, self-efficacy theory and behavioural economics, embedded within a platform supported by motivational features and gamification. The primary endpoint is defined as achieving at least a minimal clinically important difference in arthritis-related self-efficacy (the ASES-score) at the follow-up visit in favour of the intervention group when compared to the control group.

Moreover, although qualitative studies have highlighted concerns among both patients and healthcare professionals that mobile apps might induce illness behaviour by increasing patients' awareness of their symptoms, this has rarely been studied in detail. Consequently, data regarding the effects of remote monitoring on symptom hypervigilance remain limited and conflicting. Therefore, this trial additionally aims to assess (as a key secondary objective) if a mobile app-based intervention is associated with changes in pain catastrophising, as a conceptualisation of hypervigilance to symptoms.

Registry
clinicaltrials.gov
Start Date
March 3, 2023
End Date
February 29, 2024
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Arthritis Self-Efficacy Scale (ASES)

Time Frame: At follow-up visit (4-6 months from baseline)

Superiority outcome. The ASES is a patient-reported questionnaire consisting of 20 items across 2 subscales: self-efficacy for managing pain (range 5-50), and self-efficacy for controlling other symptoms (range 6-60). Both scores can be summed to derive a total ASES-score (range 11-110). Higher scores indicate higher perceived self-efficacy.

Secondary Outcomes

  • Pain Catastrophizing Scale (PCS)(At follow-up visit (4-6 months from baseline))
  • Rheumatoid Arthritis Impact of Disease (RAID)(At follow-up visit (4-6 months from baseline))
  • International Physical Activity Questionnaire Short Form (IPAQ-S)(At follow-up visit (4-6 months from baseline))
  • Pittsburgh Sleep Quality Index (PSQI)(At follow-up visit (4-6 months from baseline))

Study Sites (2)

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