Swiss Postpartum Hypertension Cohort (Swiss-PPHT)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 480
- 试验地点
- 1
- 主要终点
- Frequency of persistent hypertension defined by 24 hours BP measurement
研究概览
简要总结
This open label, prospective observational, single-center registry is to study short-, intermediate-and long-term course of postpartum hypertension and predictors/risk factors associated with long term cardiovascular and renal risk.
Current disease management strategies will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •all women with hypertensive disorders of pregnancy
- •postpartum hypertension (blood pressure measurements of systolic ≥140 and/or diastolic ≥ 90mmHg or antihypertensive therapy within the first 14 days after delivery)
- •women with preexisting hypertension or
- •women on antihypertensive medication
排除标准
- •delivery > 14 days
- •lack of consent to participate in the study, language barriers or lack of general understanding
结局指标
主要结局
Frequency of persistent hypertension defined by 24 hours BP measurement
时间窗: through study completion, an average of 5 years
Frequency of persistent hypertension defined by 24 hours BP measurement
Frequency of persistent hypertension defined by office blood pressure measurement (OBPM, AOBPM)
时间窗: through study completion, an average of 5 years
Frequency of persistent hypertension defined by office blood pressure measurement (OBPM, AOBPM)
Frequency of microalbuminuria
时间窗: through study completion, an average of 5 years
Frequency of microalbuminuria
Frequency of damage to the retina of the eyes (retinopathy)
时间窗: through study completion, an average of 5 years
Frequency of damage to the retina of the eyes (retinopathy)
Signs of hypertensive heart disease
时间窗: up to 24 months
Signs of hypertensive heart disease at transthoracic echocardiography determined by left ventricular hypertrophy (LVH)
Frequency of dyslipidemia
时间窗: through study completion, an average of 5 years
Frequency of dyslipidemia
Frequency of prediabetes/diabetes
时间窗: through study completion, an average of 5 years
Frequency of prediabetes/diabetes
次要结局
未报告次要终点