Exploring the Links Between Hearing, Cognition and Brain Activity in People With Tinnitus
Not Applicable
Not yet recruiting
- Conditions
- Tinnitus
- Registration Number
- NCT06940726
- Lead Sponsor
- Institut Pasteur
- Brief Summary
The goal of this observational study is to understand the mechanisms underlying tinnitus, and improve the clinical assessment strategies needed to develop targeted therapeutic interventions by comparing endogenous attention capacities in healthy subjects and subjects with tinnitus
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 114
Inclusion Criteria
- Age ≥ 18 years
- Good written and oral comprehension of the French language
- Normal or corrected vision
Group of people with tinnitus :
- Chronic tinnitus > 3 months, uni or bilateral, stable (no period of remission)
Control group :
- No tinnitus
Exclusion Criteria
- Presence of a known neurological disorder
- Presence of a known degenerative pathology
- Presence of a known hearing impairment
- Presence of a motor disability of the upper limbs
- Severe or profound deafness on one or both sides
- Person under legal protection (guardianship, curatorship, etc.)
- Use of hearing aids
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Contingent negative variation (CNV) in EEG 2 hours
- Secondary Outcome Measures
Name Time Method Response reaction time (in ms) 2 hours Comparison of reaction time (RT) variability following response button presses in behavioural tasks
Answer accuracy (% correct answers) 2 hours Comparison of the variability of the number of correct responses following button presses in behavioural tasks.
Cerebral oscillations (alpha bands) obtained by EEG during behavioural tasks 2 hours Skin conductance (μS) 2 hours during behavioral task
Heart rate variability (in ms) 2 hours during behavioral task
Pupillometry (pupillary dilation in mm) 2 hours