COVID-19 Study on natural protection against SARS-CoV2 reinfections

• Conditions: U07.1; COVID-19, virus identified

• Registration Number: DRKS00023113
• Lead Sponsor: Institut für VirologieUniversitätklinikum Bonn

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-22
• Study Completion: 2021-11-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 1429

Inclusion Criteria

Consenting subjects who agree to participate in the study, regardless of age and acute or previous COVID-19 infection
Registered residents of the defined municipalities, either:
- Selection based on the COVID-19 Case Cluster Study (high prevalence Heinsberg district), or
- randomly selected index persons by the municipal administration of Rheinbach (low-prevalence region) from the population registration data regardless of age and regardless of an acute or previous COVID-19 infection, as well as their household members

Exclusion Criteria

Refusal of informed consent.
Contraindication for the described specimen collection methods (venipuncture or capillary blood collection via fingertip or throat swab)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint is the prevalence of SARS/CoV-2 positive individuals in the study populations, defined as the number of participants with positive laboratory results (from at least one of the sample media taken in the study; the IgA value is excluded here because this test from the company Euroimmun has too low sensitivity and specificity) divided by the total number of study participants in the study period as well as the increase in new infections in the population of the already SARS-CoV-2 IgG/total antibody/PCR positive and the previously SARS-CoV-2 IgG/total antibody/PCR negative population.<br>