A study comparing 2 drugs in reversal of general anaesthesia
Not Applicable
- Registration Number
- CTRI/2023/10/058419
- Lead Sponsor
- SIMS hospitals, Department of anaesthesiology and pain management
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA Grade 1 and 2, all patients willing to participate in the study who are undergoing surgery lasting 1 to 2 hours requiring general anaesthesia
Exclusion Criteria
ASA grade 3 and 4, BMI > 30, deranged liver function, deranged renal function, anatomical malformations in airway, history of malignant hyperthermia, history of neuromuscular disorders, allergy to any general anaesthesia medications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the time of reversal from rocuronium induced neuromuscular blockade between neostigmine- glycopyrrolate and sugammadexTimepoint: To compare the time of extubation from rocuronium induced neuromuscular blockade between neostigmine- glycopyrrolate and sugammadex after administration of each agent in that specific group of patients
- Secondary Outcome Measures
Name Time Method To compare haemodynamic changes safety & hypersensitivity reactions & need for rescue reversal between neostigmine- glycopyrrolate & sugammadexTimepoint: Heart rate & Blood pressure & oxygen saturation monitoring every minute during extubation & every 15 minutes for 2 hours post extubation