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Clinical Trials/CTRI/2025/05/087580
CTRI/2025/05/087580Not yet recruitingNot Applicable

Predictors of High Flow Nasal Cannula Failure in Children Admitted to Paediatric Intensive Care Unit

Brinda M1 site in 1 country60 target enrollmentStarted: March 6, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
60
Locations
1
Primary Endpoint
1. To identify the predictors of HFNC failure

Study Overview

Brief Summary

High Flow Nasal Cannula(HFNC) is a valuable respiratory support technique for adults, children, newborns, and infants. HFNC offers benefits over traditional oxygen therapy in the areas of humidification, oxygenation,CO2 clearance, and reduces respiratory distress. It is necessary to know the predictors of failure to guide the therapy. Data will be collected retrospectively from the medical records and will be analyzed to find the predictors of HFNC failure. Outcomes of HFNC and length of stay will be documented. The primary outcome is to identify the predictors of HFNC failure. The secondary outcomes are: To determine the threshold value of each parameter that is S/F ratio, p-ROX, PRESS score and to assess the outcomes of children on HFNC ( mortality). Hence, the results of this study will help in finding the parameters that will guide HFNC therapy.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
1.00 Month(s) to 18.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Children aged 1 month to 18 years experienced Respiratory distress of any cause and have received HFNC Therapy.

Exclusion Criteria

  • Children with Chronic lung Disease and Congenital Cyanotic Heart Disease and files with incomplete data.

Outcomes

Primary Outcomes

1. To identify the predictors of HFNC failure

Time Frame: 1. 1hr, 4hr, 12hrs after initiation of HFNC.

Secondary Outcomes

  • -To determine the threshold value of each parameter that is S/F ratio, p-ROX, PRESS score.(-To assess the outcomes of children on HFNC)

Investigators

Sponsor
Brinda M
Sponsor Class
Other [self]

Study Sites (1)

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