EFFECT OF INVASIVE VS NON INVASIVE MODE OF HUMIDIFICATION.

Phase 3

Completed

Conditions: Other specified respiratory disorders,

Registration Number: CTRI/2023/05/052333

Lead Sponsor: Dr Srinivas Murki

Brief Summary: All term infants admitted with respiratory distress and requires non invasive mode of ventilation(either CPAP or HFNC) will be given non invasive mode of humidification which is low temperature(34C) and low humidity(>30mg/L) in the intervention arm and Invasive mode of humidification i.e. high temperature(37C) , high humidity(44mg/L) in control arm. both thiese modes of humidification are present on all standard humidifier (Fischer and Packel MR 850 i.n this case). Both modes will supply absolute humidity of >30mg/L and temperature of > 30C which is usual recommendation.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 104

Inclusion Criteria

Term infants admitted in NICU requiring primary non invasive respiratory support.

Exclusion Criteria

1.Babies with congenital anomalies 2.Syndromic babies 3.Neonates receiving therapeutic hypothermia 4.Neonates in whom primary mode of respiratory support is invasive.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total duration of respiratory support during admission to the NICU	Till hospital discharged.

Secondary Outcome Measures

Name	Time	Method
1. Ventilator Associated Pneumonia	2. Humidity and Temperature at nasopharyngeal level (thermohygrometer)

Trial Locations

Locations (1): Paramitha Children Hospital
🇮🇳
Hyderabad, TELANGANA, India
Paramitha Children Hospital
🇮🇳Hyderabad, TELANGANA, India
Dr Srinivas Murki
Principal investigator
9392470351
srinivasmurki2001@gmail.com