Comparing regimens ( Bismuth sub-citrate , Omeprazole , Amoxicillin , Clarithromycin , Tinidazole ) and ( Bismuth sub citrate , Omeprazole , Tetracycline , Metronidazole , Ofloxacin ) on the eradication rate of Helicobacter pylori infection in non responder dyspeptic patients
Phase 2
- Conditions
- dyspepsia.Dyspepsia
- Registration Number
- IRCT201103011155N11
- Lead Sponsor
- Vince chancellor for reaserch guilan univercity of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Inclusion: In this study , helicobacter pylori positive patients over 15 years and less than 65 years that under drug treatment regiment quadriple or triple placed urea breath test (UBT) using carbon 14 (C14 or C13 or stoolAg) with the European protocol again have been positive , will enter the study.
Exclusion : Pregnant women , Patients with gastric malignancy , Cirrhosis , Patients with allergy to Amoxicillin or Clarithromycin , Omeprazole , Tetracycline , Ofloxacin , Metronidazole and Tinidazole , Colestramin Consumption , Renal failure , History of seizures , Blood disorders , Fauvism and treatment of patients with incomplete (less than 80%) will be excluded.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Helicobacter pylori eradication. Timepoint: 12 week. Method of measurement: ureas breath test with c14 and stool antigen.
- Secondary Outcome Measures
Name Time Method