Evaluating the efficacy of subcutaneous nitroglycerine infiltration for trans radial access in improving the success rate and reducing early radial artery occlusion. A randomised double blind placebo controlled trial.
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 344
- 试验地点
- 1
- 主要终点
- 1. Improvement in success rate of Trans radial access with the use of subcutaneous nitroglycerine
研究概览
简要总结
Transradial coronary catheterization is widely used as both diagnostic and interventional procedure for acute as well as chronic coronary syndromes. However, the access to radial artery is difficult due to spasm and also leads to radial artery occlusion. This study will evaluate the efficacy of subcutaneous Nitroglycerine Infiltration in improving the success rate and reducing early Radial Artery Occlusion using the Anterior Wall Puncture Technique for Radial Artery Access. This is a Randomized, Double-Blind, Placebo-Controlled Trial
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •1.giving written informed consent.
- •2.Patients undergoing diagnostic or therapeutic coronary catheterization via trans-radial approach.
排除标准
- •Patients with inadequate blood supply to hand (negative Allen test)
- •Hemodynamic instability
- •Peripheral arterial disease
- •Raynauds phenomenon
- •Single Hand.
结局指标
主要结局
1. Improvement in success rate of Trans radial access with the use of subcutaneous nitroglycerine
时间窗: From procedure to 24 hours
2. Prevention of Early radial artery occlusion with the use of subcutaneous nitroglycerine
时间窗: From procedure to 24 hours
次要结局
- 1. Local complications(2. Vascular complications)
研究者
ISHFAQ GULZAR BHAT
J N Medical College, AMU , Aligarh , UP