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Clinical Trials/NCT02562560
NCT02562560TerminatedNot Applicable

Neuropsycholgy and Neuroimaging in Transient Global Amnesia

University Hospital, Caen0 sites60 target enrollmentStarted: September 2008Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Terminated
Enrollment
60
Primary Endpoint
Episodic memory scores

Study Overview

Brief Summary

The purpose of this study is to establish a diagnosis in transient global amnesia (TGA) in assessing three episodic memory's abilities (mental simulation throught the future, and the past, the learning of personnal actions i-e the enactment effect). Secondary goal is to describe the neuronal substrates associated to the alteration of theses abilites in TGA.

Study Design

Study Type
Interventional
Primary Purpose
Diagnostic

Eligibility Criteria

Ages
30 Years to 90 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • All the participants
  • Minimum of 7 years of education
  • French native speaker
  • Healthy subjects : Non pathological Dementia rating scale score
  • Patients : Clinical diagnosis of TGA according to Hodges and Warlow's criterion

Exclusion Criteria

  • Chronic neurological disease
  • Encephalitis
  • Endocrinal disease
  • Hepatic disease
  • Case history of head injury with loss of consciousness of more than one hour
  • Case history of stroke
  • Case history of cancer during the five last years except squamous cell carcinomas
  • Alcoholism or drug addiction
  • Major psychiatric disorders according the Diagnostic and Statistical Manual of -Mental Disorders

Outcomes

Primary Outcomes

Episodic memory scores

Time Frame: 3 years

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

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