Neuropsycholgy and Neuroimaging in Transient Global Amnesia
Not Applicable
Terminated
- Conditions
- Transient Global Amnesia (TGA)
- Interventions
- Behavioral: Neuropsychological testsDevice: Cerebral imaging (MRI, PET-FDG)
- Registration Number
- NCT02562560
- Lead Sponsor
- University Hospital, Caen
- Brief Summary
The purpose of this study is to establish a diagnosis in transient global amnesia (TGA) in assessing three episodic memory's abilities (mental simulation throught the future, and the past, the learning of personnal actions i-e the enactment effect). Secondary goal is to describe the neuronal substrates associated to the alteration of theses abilites in TGA.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
-
All the participants
- Minimum of 7 years of education
- French native speaker
-
Healthy subjects : Non pathological Dementia rating scale score
-
Patients : Clinical diagnosis of TGA according to Hodges and Warlow's criterion
Exclusion Criteria
- Chronic neurological disease
- Encephalitis
- Endocrinal disease
- Hepatic disease
- Case history of head injury with loss of consciousness of more than one hour
- Case history of stroke
- Case history of cancer during the five last years except squamous cell carcinomas
- Alcoholism or drug addiction
- Major psychiatric disorders according the Diagnostic and Statistical Manual of -Mental Disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Controls Neuropsychological tests - TGA Cerebral imaging (MRI, PET-FDG) - TGA Neuropsychological tests - Controls Cerebral imaging (MRI, PET-FDG) -
- Primary Outcome Measures
Name Time Method Episodic memory scores 3 years
- Secondary Outcome Measures
Name Time Method