Autologous Nanofat Grafting by Injection Versus With Microneedling in Post-burn and Traumatic Atrophic Scars
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- change in the scar by by the patient and observer scar assessment scale (POSAS).
研究概览
简要总结
This study aims to evaluate the efficiency autologous nanofat injection versus autologous nanofat delivered by microneedling in management of post burn atrophic and traumatic scars.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1. Males and females between 18-60 years old.
- •Post-burn or traumatic atrophic scar > 6 months duration (16).
- •Patients not receiving any treatments for the scar within the past 3 months.
排除标准
- •1. Patients with contractures, hypertrophic and keloid scars.
- •Patients with history of bleeding disorders or coagulopathy, or on anticoagulant therpy.
- •3. Diabetes and other systemic diseases that may be complicated by the procedure.
- •4. Pregnant and lactating females.
- •BMI less than 18.5
- •Patients with scars at the donor site
研究组 & 干预措施
injection of autologous nanofat grafting
Two separate scars with similar properties or splitting of one large post-burn atrophic scar. One (part of the) scar will be treated by injection of autologous nanofat grafting and the other (part of the) scar will be treated by microneedling with autologous nanofat graft.
干预措施: injection of autologous nanofat grafting (Procedure)
microneedling with autologous nanofat graft
Two separate scars with similar properties or splitting of one large post-burn atrophic scar. One (part of the) scar will be treated by injection of autologous nanofat grafting and the other (part of the) scar will be treated by microneedling with autologous nanofat graft.
干预措施: microneedling with autologus nanofat graft (Procedure)
结局指标
主要结局
change in the scar by by the patient and observer scar assessment scale (POSAS).
时间窗: 6 months after the proceedure
patient and observer scar assessment scale score will be uesd
次要结局
未报告次要终点
研究者
Dalia Ibrahim Halwag
Principal investigator
Alexandria University